Laukoetter MG, Bruewer M, Nusrat A: Regulation of the intestinal epithelial barrier by the apical junctional complex. Curr Opin Gastroenterol 2006, 22:85–89.CrossRefPubMed 28. Saadat I, Higashi H, Obuse C, Umeda M, Murata-Kamiya
N, Saito Y, Lu H, P505-15 solubility dmso Ohnishi N, Azuma T, Suzuki A, et al.:Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity. Nature 2007, 447:330–333.CrossRefPubMed 29. Boudeau J, Glasser AL, Masseret E, Joly B, Darfeuille-Michaud A: Invasive ability of an Escherichia coli strain isolated from the ileal mucosa of a patient with Crohn’s disease. Infect Immun 1999, 67:4499–4509.PubMed 30. Neish AS: Microbes in gastrointestinal health and disease. Gastroenterology 2009, 136:65–80.CrossRefPubMed 31. Su L, Shen L, Clayburgh DR, Nalle see more SC, Sullivan EA, Meddings JB, Abraham C, Turner JR: Targeted epithelial tight junction dysfunction causes immune activation and contributes to development of experimental colitis. Gastroenterology 2009, 136:551–563.CrossRefPubMed 32. Barnich N, Darfeuille-Michaud A: Adherent-invasive Escherichia coli and Crohn’s disease. Curr Opin Gastroenterol 2007, 23:16–20.CrossRefPubMed 33. Gray-Owen SD, Blumberg RS: CEACAM1: contact-dependent control
of immunity. Nat Rev Immunol 2006, 6:433–446.CrossRefPubMed 34. Sasaki M, Sitaraman SV, Babbin BA, Gerner-Smidt P, Ribot EM, Garrett N, Alpern JA, Akyildiz A, Theiss AL, Nusrat A, et al.: Invasive Escherichia coli are a feature of Crohn’s disease. Lab Invest
2007, 87:1042–1054.CrossRefPubMed 35. Ivanov AI, Hunt D, Utech M, Nusrat A, Parkos CA: Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional many complex. Mol Biol Cell 2005, 16:2636–2650.CrossRefPubMed 36. Bagnoli F, Buti L, Tompkins L, Covacci A, Amieva MR:Helicobacter pylori CagA induces a transition from polarized to invasive phenotypes in MDCK cells. Proc Natl Acad Sci USA 2005, 102:16339–16344.CrossRefPubMed 37. Eaves-Pyles T, Allen CA, Taormina J, Swidsinski A, Tutt CB, Jezek GE, Islas-Islas M, Torres AG:Escherichia coli isolated from a Crohn’s disease patient adheres, invades, and induces inflammatory responses in polarized intestinal epithelial cells. Int J Med Microbiol 2008, 298:397–409.CrossRefPubMed 38. Hanajima-Ozawa M, Matsuzawa T, Fukui A, Kamitani S, Ohnishi H, Abe A, Horiguchi Y, Miyake M: Enteropathogenic Escherichia coli, Shigella flexneri, and Listeria monocytogenes recruit a junctional protein, zonula occludens-1, to actin tails and pedestals. Infect Immun 2007, 75:565–573.CrossRefPubMed 39. Wine E, Chan VL, Sherman PM:Campylobacter jejuni mediated disruption of polarized epithelial monolayers is cell-type specific, time dependent, and correlates with bacterial invasion. Pediatr Res 2008, 64:599–604.CrossRefPubMed 40. Monteville MR, Konkel ME: Fibronectin-facilitated invasion of T84 eukaryotic cells by Campylobacter jejuni occurs preferentially at the basolateral cell surface.