In patients with platinum-resistant and even platinum-refractory disease the response rate (of AZD0156 solubility dmso PARP inhibitor, olaparib) was of 41.7% and 15.4%, respectively [44]. Olaparib (AZD2281) was tested in BRCA-mutated patients with ovarian, primary peritoneal, and fallopian tube cancer. In the study, 20 patients (40%) responded to the therapy. Currently, randomized trials of olaparib and other PARP inhibitors in patients with learn more Ovarian cancer are underway. Conclusion Maximal surgical cytoreduction followed by systemic taxane and platinum-based chemotherapy is the standard treatment for patients with ovarian
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