If limited surgery is indicated for solid subcentimetre lung cancer, a thorough intraoperative evaluation of lymph nodes is needed to prevent loco-regional failure.”
“Background: Prescribing is a complex task with potential for many types of error to occur. Despite JNJ-26481585 manufacturer the introduction of a standard national medication chart for Australian hospital inpatients in 2006, simple prescribing errors are common. Aim: To compare the effect of quality improvement initiatives on the rate of simple prescribing errors. Design: A prospective, multisite comparison of prescribing education interventions. Methods: Using three hospital sites, we compared site-specific changes in prescribing
error rates following use of an online education module alone (low intensity) with prescribing error rates following a high-intensity intervention (comprising the same online education module plus nurse education and academic detailing of junior prescribers). The study period was 4 months between May and August 2011. Results: Full completion of the adverse drug reactions field did not improve after either intervention; however, there was better documentation of some elements following high-intensity
intervention. Prescriber performance improved significantly for more elements in the regular prescription category than any other category of prescription. Legibility of medication name improved across all categories following interventions. Clarity of frequency, prescriber name and documentation of indication improved following both high- and low-intensity intervention. CP-456773 ic50 Conclusions: Improvements were seen in several prescription elements after the intervention but the majority of elements that improved were affected by both low- and high-intensity interventions. Despite targeted intervention, significant rates of prescribing breaches persisted. The prevalence of prescription breaches partially responds to an online education module. The nature of any additional intervention that would be effective is unclear.”
“Wang F, Dennis JE, Awadallah A, Solchaga LA, Molter J, Kuang Y, Salem N, Lin Y, Tian H, Kolthammer JA, Kim Y, Love ZB, Gerson
SL, Lee Z. Transcriptional profiling find more of human mesenchymal stem cells transduced with reporter genes for imaging. Physiol Genomics 37: 23-34, 2009. First published December 30, 2008; doi: 10.1152/physiolgenomics.00300.2007.-Mesenchymal stem cells (MSCs) can differentiate into osteogenic, adipogenic, chondrogenic, myocardial, or neural lineages when exposed to specific stimuli, making them attractive for tissue repair and regeneration. We have used reporter gene-based imaging technology to track MSC transplantation or implantation in vivo. However, the effects of lentiviral transduction with the fluc-mrfp-ttk triple-fusion vector on the transcriptional profiles of MSCs remain unknown. In this study, gene expression differences between wild-type and transduced hMSCs were evaluated using an oligonucleotide human microarray.