03). There were no differences in changes in HRQOL scores between the groups over 3 months.
Conclusions: Positive effects of the intervention on survival were found. However, there was no significant difference in changes in HRQOL.”
“In this study, the effect of the dopant structure on the morphology, structure, optical absorption, conductivity, and thermal properties of conductive polyaniline (PAn)/silica (SiO(2)) hybrids from a sol-gel process was
first investigated. Camphorsulfonic acid (CSA) and dodecylbenzylsulfonic acid (DBSA) were used as the model acid dopants. The polaron absorption peaks of the CSA-doped PAn/SiO(2) (CSA-PAn/SiO(2)) hybrids were redshifted compared with those of the DBSA-PAn/SiO(2) hybrids. This indicated that the doped PAn subchains of the CSA-PAn/SiO(2) hybrids had
a more rigid conformation check details and longer conjugation length than those of DBSA-PAn/SiO(2) hybrids. Therefore, the CSA-PAn/SiO(2) hybrids were more conductive than the DBSA-PAn/SiO(2) INCB028050 inhibitor hybrids with same SiO(2) contents. Moreover, the CSAPAn/SiO(2) hybrids exhibited higher SiO(2) condensation degrees and thermal resistance than the DBSA-PAn/SiO(2) hybrids with same SiO(2) contents. In addition, the CSAPAn/SiO(2) films exhibited a nonuniform globular morphology, whereas the DBSA-PAn/SiO(2) films showed an interconnected and rugged fibrillar one. (C) 2009 Wiley Periodicals, Inc. J Appl Polym Sci 116: 934-945, 2010″
“P>The integrity of the genome is a fundamental prerequisite for the well-being of all living
organisms. Critical for the genomic integrity are effective DNA damage detection mechanisms that enable the cell to rapidly activate the necessary repair machinery. Here, we describe Arabidopsis thaliana ATCSA-1, which is an ortholog of the mammalian Cockayne Syndrome type-A protein involved in transcription-coupled DNA repair processes. ALK inhibitor ATCSA-1 is a critical component for initiating the repair of UV-B-induced DNA lesions, and, together with the damage-specific DNA binding protein 2 (DDB2), is necessary for light-independent repair processes in Arabidopsis. The transcriptional profile of both genes revealed that ATCSA-1 is strongly expressed in most tissues, whereas DDB2 is only weakly expressed, predominantly in the root tips and anthers of flowers. In contrast to ATCSA-1, DDB2 expression is rapidly inducible by UV treatment. Like DDB2, ATCSA-1 is localized to the nucleus, and assembles with DDB1 and CUL4 proteins into a complex. ATCSA-1 is an unstable protein that is degraded in a 26S proteasome-dependent manner. Overall, the results presented here form a functional description of a plant Cockayne syndrome factor A (CSA) ortholog, and demonstrate the importance of ATCSA-1 for UV-B tolerance.”
“Purpose: To prospectively determine clinical value of dynamic contrast material-enhanced magnetic resonance (MR) imaging in the evaluation of disease activity in perianal Crohn disease (CD).