In this method, a weighted linear regression is run on the points

BMC/BMD/BMAD values adjusted by the nonlinear regression model were used to estimate the age at peak bone mineral JAK inhibitor review content/density. Additional robust nonparametric smoothing techniques were used to provide the estimate as a function of age [24]. In this method, a weighted linear regression is run on the points surrounding the one of interest and the predicted

value is obtained. The models were fit using the STATA’s nl module (version 9, Stata Corporation, College this website Station, TX, USA). Chronological age, age at menarche, percent body fat, alcohol use, and weight-bearing exercise find more did not differ among the three racial/ethnic groups (Table 1). Table 1 Characteristics of study participants by race/ethnicity Characteristic Black (n = 204) White (n = 247) Hispanic (n = 257) Significant differencesa Age, %       NS 16–24 years 57.4 51.0 50.6   25–33 years 42.6 49.0 49.4   Height, cm, mean (SE) 162.8 (0.5) 164.1 (0.4) 158.4

(0.4) W, B>H Weight, kg, mean (SE) 78.5 (1.5) 70.5 (1.1) 70.0 (1.0) B>W, H BMI (kg/m2), mean (SE) 29.6 (0.5) 26.2 (0.4) 27.8 (0.4) B> H>W Lean mass, kg, GBA3 mean (SE) 48.1 (0.6) 43.4 (0.4) 42.1 (0.4) B>W, H Fat mass, kg, mean (SE) 28.4 (1.0) 25.4 (0.7) 26.1 (0.6) B>W Fat mass, percent of total, mean (SE) 35.2 (0.6) 35.3 (0.5) 37.0 (0.4) NS Age at menarche, year, mean 12.2 (0.1) 12.4 (0.1) 12.3 (0.1) NS Ever married, % 15.7 43.7 49.4 W, H>B Parity, mean 1.12 (0.08) 0.96 (0.07) 1.40 (0.08) H>B, W Ever lactated, %b 30.4 59.7 55.4 W, H>B Months of pill use 15.0 (1.8) 25.5 (2.3) 15.5 (1.6) W>B, H Months of DMPA use 10.2 (1.3) 4.0 (0.7) 6.1 (1.0) B>W, H High school graduate, % 74.5 84.6 70.8 W>B, H Relative with shortened height, %c 12.0 42.9 40.2 W, H>B Relative with fracture history, %d 3.5 21.5 14.5 W, H>B Current smoker, % 16.2 39.3 24.9 W>H>B Alcohol intake, g/day, mean (SE) 0.9 (0.6) 2.4 (0.9) 1.5 (0.4) NS Calcium intake, mg/day, mean (SE) 575 (28) 663 (21) 629 (21) W>B Weight-bearing exercise >120 min/week, % 33.8 32.4 44.9 NS Spine BMC, g 60.9 (0.7) 60.1 (0.6) 55.5 (0.5) B, W>H Spine BMD, g/cm2, mean (SE) 1.101 (0.008) 1.044 (0.006) 1.031 (0.006) B>W, H Spine BMAD, g/cm3, mean (SE) 0.149 (0.001) 0.138 (0.001) 0.141 (0.001) B>H>W Femoral neck BMC, g 4.3 (0.06) 4.1 (0.04) 4.0 (0.

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