135. Shin NR, Jeong EH, Choi CI, Moon HJ, Kwon CH, Chu IS, Kim GH, Jeon TY, Kim DH, Lee JH, Park do Y: Overexpression of
Snail is associated with lymph node metastasis and poor prognosis in patients with gastric cancer. BMC Cancer 2012, 12:521.SYN-117 purchase PubMedCentralPubMed mTOR activity 136. Yokoyama K, Kamata N, Hayashi E, Hoteiya T, Ueda N, Fujimoto R, Nagayama M: Reverse correlation of E-cadherin and snail expression in oral squamous cell carcinoma cells in vitro. Oral Oncol 2001, 37:65–71.PubMed 137. Hotz B, Arndt M, Dullat S, Bhargava S, Buhr HJ, Hotz HG: Epithelial to mesenchymal transition: expression of the regulators snail, slug, and twist in pancreatic cancer. Clin Cancer Res 2007, 13:4769–4776.PubMed 138. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ: Cancer statistics, 2009. CA Cancer J Clin 2009, 59:225–249.PubMed
139. Roy H, Smyrk T, Koetsier J, Victor T, Wali R: The transcriptional repressor SNAIL is overexpressed in human colon cancer. Dig Dis Sci 2005, 50:42–46.PubMed 140. Fan F, Samuel S, Evans KW, Lu J, Xia L, Zhou Y, Sceusi E, Tozzi F, Ye XC, Mani SA, Ellis LM: Overexpression of Snail induces epithelial-mesenchymal transition and a cancer stem cell-like phenotype in human colorectal cancer cells. Cancer Med 2012, 1:5–16.PubMedCentralPubMed 141. Yu Q, Zhang K, Wang X, Liu X, Zhang Z: Expression of transcription factors snail, slug, and twist in human bladder carcinoma. J Exp Clin Cancer Res 2010, 29:119.PubMedCentralPubMed HSP inhibitor 142. Bruyere F, Namdarian B, Corcoran NM, Pedersen J, Ockrim J, Voelzke BB, Mete U, Costello AJ, Hovens CM: Snail expression is an independent predictor of tumor recurrence in superficial bladder cancers. Urol Oncol 2010, 28:591–596.PubMed 143. Poser I, Dominguez D, Garcia de Herreros A, Varnai A, Buettner R, Bosserhoff AK: Loss of E-cadherin expression
in melanoma cells involves up-regulation of the transcriptional repressor Snail. J Biol Chem 2001, 276:24661–24666.PubMed 144. Kudo-Saito C, Shirako H, Takeuchi T, Kawakami Y: Cancer metastasis is accelerated through immunosuppression during Snail-induced EMT of cancer cells. Cancer Cell 2009, 15:195–206.PubMed 145. Saito T, Oda Y, Tsuneyoshi M: E-cadherin gene mutations frequently occur in synovial sarcoma as a determinant of histological features. Am J Pathol 2001, 159:2117–2124.PubMedCentralPubMed 146. Jemal A, Bray F, Center MM, 3-mercaptopyruvate sulfurtransferase Ferlay J, Ward E, Forman D: Global cancer statistics. CA Cancer J Clin 2011, 61:69–90.PubMed 147. Delahunt B, Miller RJ, Srigley JR, Evans AJ, Samaratunga H: Gleason grading: past, present and future. Histopathology 2012, 60:75–86.PubMed 148. Pecina-Slaus N: Tumor suppressor gene E-cadherin and its role in normal and malignant cells. Cancer Cell Int 2003, 3:17–18.PubMedCentralPubMed 149. Edwards IJ: Proteoglycans in prostate cancer. Nat Rev Urol 2012, 21:196–206. 150. Smith B, Odero-Marah V: The role of Snail in prostate cancer. Cell Adh Migr 2012, 6:433–441.PubMedCentralPubMed 151.