Do you know which responsibilities you have? (1) Very seldom or never (2) Seldom (3) Sometimes (4) Very often or always. Do you know exactly what

is required of you at work? (1) Very seldom or never (2) Seldom (3) Sometimes (4) Very often or always. Appreciation of being in the group (Lindström et al. 2000; Dallner et al. 2000). (1) Very little or not at all (2) Little (3) Some (4) Pretty much (5) see more Very much. The outcome variable depressive symptoms were assessed with the Hospital Anxiety and Depression Scale (HAD-depression). Response options were made on a 4-point Likert response scale (1: never; 2: sometimes, 3: often, 4: always). The scores were categorized into the three previously developed cut offs with <7: no sign of depression, 7–10 points: mild depression, 11 points and above: GS-1101 supplier clinical depression. The categories were then dichotomized into <7 no depression and >7 depressed. I appreciate the same

things as before. I can laugh and see things from the funny side. I am feeling lucky. I feel as if everything is moving slowly. I have lost interest in my appearance. I look forward to things with joy. I enjoy a good book or a good radio program or a good TV program. Statistical analysis To analyze which variables would predict symptoms of depression at T2, we did the following: based on the review of the literature, a large set of relevant work environmental, individual, and demographic risk factors, in the questionnaire, was considered to be included in the Generalized Linear Model. The variables of age, gender, and bystanding to bullying, and job strain were forced to stay fixed in the model, even if they were statistically non-significant at the 5 % level. The main reason for choosing these variables was that these factors in the work environment have previously been shown to risk factors of depression. Megestrol Acetate Variables with p-values

not above 10 % level were re-entered in the model in later steps to see if they performed better when other variables were removed. With regard to the question whether the respondent had been sexually harassed and whether the respondent had noticed if someone had been subjected to sexual harassment, the numbers were so few that we decided not to include them in the analysis. Results Figure 1 shows a schematic representation of participants in the study. The total Roscovitine manufacturer number of subjects in the four companies was n = 4,238. The total number of respondents with more than 1 year at the workplace at T1: n = 2,563 (Women: n = 342; Men: n = 2,227). Bystanders to bullying at T1, n = 305 (Women: n = 30; Men: n = 275). The total number of women with symptoms of depression at T2 was n = 30, and the total number of men with symptoms of depression at T2 was n = 161. The total number of employees who answered the questionnaire on both occasions (T1 and T2) was 2,177.